Novel [99mTcN]2+ Labeled EGFR Inhibitors as Potential Radiotracers for Single Photon Emission Computed Tomography (SPECT) Tumor Imaging

The epidermal growth factor receptor (EGFR) is overexpressed in many cancers, including breast, ovarian, endometrial and non-small cell lung cancer. An EGFR-specific imaging agent could facilitate clinical evaluation of primary tumors or metastases. To achieve this goal, 4-(2-aminoethylamino)-6,7-di...

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Bibliographic Details
Main Authors: Mingxia Zhao, Hongyu Ning, Man Feng, Shilei Li, Jin Chang, Chuanmin Qi
Format: Article
Language:English
Published: MDPI AG 2014-04-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/19/5/5508