Thermodynamic Characterization of the Ca<sup>2+</sup>-Dependent Interaction Between SOUL and ALG-2

Thermodynamic Characterization of the Ca<sup>2+</sup>-Dependent Interaction Between SOUL and ALG-2

SOUL, a heme-binding protein-2 (HEBP-2), interacts with apoptosis-linked gene 2 protein (ALG-2) in a Ca<sup>2+</sup>-dependent manner. To investigate the properties of the interaction of SOUL with ALG-2, we generated several mutants of SOUL and ALG-2 and analyzed the recombinant proteins...

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Bibliographic Details
Main Authors: Taisuke Mikasa, Masami Kugo, Seigo Nishimura, Sigeru Taketani, Sumio Ishijima, Ikuko Sagami
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:International Journal of Molecular Sciences
Subjects:
ALG-2
calcium-binding protein
SOUL
HEBP-2
heme-binding protein
thermodynamics
ITC
binding affinity
Online Access:https://www.mdpi.com/1422-0067/19/12/3802

Internet

https://www.mdpi.com/1422-0067/19/12/3802

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