Current Views of Toll-Like Receptor Signaling Pathways

On microbial invasion, the host immediately evokes innate immune responses. Recent studies have demonstrated that Toll-like receptors (TLRs) play crucial roles in innate responses that lead not only to the clearance of pathogens but also to the efficient establishment of acquired immunity by directl...

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Bibliographic Details
Main Authors: Masahiro Yamamoto, Kiyoshi Takeda
Format: Article
Language:English
Published: Hindawi Limited 2010-01-01
Series:Gastroenterology Research and Practice
Online Access:http://dx.doi.org/10.1155/2010/240365