A novel role for the ADHD risk gene latrophilin-3 in learning and memory in Lphn3 knockout rats

Latrophilins (LPHNs) are adhesion G protein-coupled receptors with three isoforms but only LPHN3 is brain specific (caudate, prefrontal cortex, dentate, amygdala, and cerebellum). Variants of LPHN3 are associated with ADHD. Null mutations of Lphn3 in rat, mouse, zebrafish, and Drosophila result in h...

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Bibliographic Details
Main Authors: Samantha L. Regan, Emily M. Pitzer, Jillian R. Hufgard, Chiho Sugimoto, Michael T. Williams, Charles V. Vorhees
Format: Article
Language:English
Published: Elsevier 2021-10-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996121002059