The construction of a novel xenograft bovine bone scaffold, (DSS)6-liposome/CKIP-1 siRNA/calcine bone and its osteogenesis evaluation on skull defect in rats

Background: Xenograft bone scaffolds have advantages such as mechanical strength, sufficient source and safety. Combined with siRNA properly targeting CKIP-1, a negative regulator of osteogenesis, may contribute to the repair result of calcine bone alone. Methods: Herein, we constructed a novel xeno...

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Bibliographic Details
Main Authors: Gang Xu, Xiantong Hu, Liwei Han, Yantao Zhao, Zhonghai Li
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:Journal of Orthopaedic Translation
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2214031X21000073