The microRNAs in an ancient protist repress the variant-specific surface protein expression by targeting the entire coding sequence.
microRNAs (miRNA) have been detected in the deeply branched protist, Giardia lamblia, and shown to repress expression of the family of variant-specific surface proteins (VSPs), only one of which is expressed in Giardia trophozoite at a given time. Three next-generation sequencing libraries of Giardi...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2014-02-01
|
| Series: | PLoS Pathogens |
| Online Access: | http://europepmc.org/articles/PMC3937270?pdf=render |