Nanostructures of diamond, graphene oxide and graphite inhibit CYP1A2, CYP2D6 and CYP3A4 enzymes and downregulate their genes in liver cells

Nanostructures of diamond, graphene oxide and graphite inhibit CYP1A2, CYP2D6 and CYP3A4 enzymes and downregulate their genes in liver cells

Barbara Strojny,1 Ewa Sawosz,1 Marta Grodzik,1 Sławomir Jaworski,1 Jarosław Szczepaniak,1 Malwina Sosnowska,1 Mateusz Wierzbicki,1 Marta Kutwin,1 Sylwia Orlińska,1 André Chwalibog2 1Division of Nanobiotechnology, Warsaw University of Life Sciences, Warsaw, Poland; 2Department of Veterina...

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Bibliographic Details
Main Authors: Strojny B, Sawosz E, Grodzik M, Jaworski S, Szczepaniak J, Sosnowska M, Wierzbicki M, Kutwin M, Orlińska S, Chwalibog A
Format: Article
Language:English
Published: Dove Medical Press 2018-12-01
Series:International Journal of Nanomedicine
Subjects:
carbon nanostructures
nanoparticles
cytochrome P450
microsomes
liver
Online Access:https://www.dovepress.com/nanostructures-of-diamond-graphene-oxide-and-graphite-inhibit-cyp1a2-c-peer-reviewed-article-IJN

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https://www.dovepress.com/nanostructures-of-diamond-graphene-oxide-and-graphite-inhibit-cyp1a2-c-peer-reviewed-article-IJN

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