Cytotoxic and toxicological effects of phthalimide derivatives on tumor and normal murine cells

Cytotoxic and toxicological effects of phthalimide derivatives on tumor and normal murine cells

Eleven phthalimide derivatives were evaluated with regards to their antiproliferative activity on tumor and normal cells and possible toxic effects. Cytotoxic analyses were performed against murine tumors (Sarcoma 180 and B-16/F-10 cells) and peripheral blood mononuclear cells (PBMC) using MTT and A...

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Main Authors: PAULO MICHEL PINHEIRO FERREIRA, PATRICIA MARÇAL DA COSTA, ARINICE DE MENEZES COSTA, DAISY JEREISSATI BARBOSA LIMA, RENATA ROSADO DRUMOND, JURANDY DO NASCIMENTO SILVA, DIOGO RODRIGO DE MAGALHÃES MOREIRA, GEVÂNIO BEZERRA DE OLIVEIRA FILHO, JAMILE MAGALHÃES FERREIRA, MARIA GORETTI RODRIGUES DE QUEIROZ, ANA CRISTINA LIMA LEITE, CLÁUDIA PESSOA
Format: Article
Language:English
Published: Academia Brasileira de Ciências 2015-03-01
Series:Anais da Academia Brasileira de Ciências
Subjects:
alterações histológicas
células murinas
citotoxicidade
derivados da ftalimida
sarcoma 180
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652015000100313&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652015000100313&lng=en&tlng=en

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