Etv transcription factors functionally diverge from their upstream FGF signaling in lens development

Etv transcription factors functionally diverge from their upstream FGF signaling in lens development

The signal regulated transcription factors (SRTFs) control the ultimate transcriptional output of signaling pathways. Here, we examined a family of FGF-induced SRTFs – Etv1, Etv 4, and Etv 5 – in murine lens development. Contrary to FGF receptor mutants that displayed loss of ERK signaling and defec...

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Bibliographic Details
Main Authors: Ankur Garg, Abdul Hannan, Qian Wang, Neoklis Makrides, Jian Zhong, Hongge Li, Sungtae Yoon, Yingyu Mao, Xin Zhang
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-02-01
Series:eLife
Subjects:
FGF
ETS
PEA3
Notch
mTOR
lens development
Online Access:https://elifesciences.org/articles/51915

Internet

https://elifesciences.org/articles/51915

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