A Combination Adjuvant for the Induction of Potent Antiviral Immune Responses for a Recombinant SARS-CoV-2 Protein Vaccine

A Combination Adjuvant for the Induction of Potent Antiviral Immune Responses for a Recombinant SARS-CoV-2 Protein Vaccine

Several SARS-CoV-2 vaccines have received EUAs, but many issues remain unresolved, including duration of conferred immunity and breadth of cross-protection. Adjuvants that enhance and shape adaptive immune responses that confer broad protection against SARS-CoV-2 variants will be pivotal for long-te...

Full description

Bibliographic Details
Main Authors: Sonia Jangra, Jeffrey J. Landers, Raveen Rathnasinghe, Jessica J. O’Konek, Katarzyna W. Janczak, Marilia Cascalho, Andrew A. Kennedy, Andrew W. Tai, James R. Baker, Michael Schotsaert, Pamela T. Wong
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Immunology
Subjects:
SARS-CoV-2
intranasal vaccine
mucosal adjuvant
cross-protection
nanoemulsion (NE)
RIG-I agonist
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.729189/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.729189/full

Similar Items