Neonatal hyperglycemia inhibits angiogenesis and induces inflammation and neuronal degeneration in the retina.

Recent evidence suggests that transient hyperglycemia in extremely low birth weight infants is strongly associated with the occurrence of retinopathy of prematurity (ROP). We propose a new model of Neonatal Hyperglycemia-induced Retinopathy (NHIR) that mimics many aspects of retinopathy of prematuri...

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Bibliographic Details
Main Authors: Elsa Kermorvant-Duchemin, Alexis Christophe Pinel, Sophie Lavalette, Delphine Lenne, William Raoul, Bertrand Calippe, Francine Behar-Cohen, José-Alain Sahel, Xavier Guillonneau, Florian Sennlaub
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3836846?pdf=render