Geminin is required for zygotic gene expression at the Xenopus mid-blastula transition.

In many organisms early development is under control of the maternal genome and zygotic gene expression is delayed until the mid-blastula transition (MBT). As zygotic transcription initiates, cell cycle checkpoints become activated and the tempo of cell division slows. The mechanisms that activate z...

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Bibliographic Details
Main Authors: Sarah L Kerns, Kathryn M Schultz, Kelly A Barry, Tina M Thorne, Thomas J McGarry
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3360639?pdf=render