Dendrimer size effects on the selective brain tumor targeting in orthotopic tumor models upon systemic administration

Abstract Malignant gliomas are the most common and aggressive form of primary brain tumors, with a median survival of 15–20 months for patients receiving maximal interventions. Advances in nanomedicine have provided tumor‐specific delivery of chemotherapeutics to potentially overcome their off‐targe...

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Bibliographic Details
Main Authors: Kevin Liaw, Fan Zhang, Antonella Mangraviti, Sujatha Kannan, Betty Tyler, Rangaramanujam M. Kannan
Format: Article
Language:English
Published: Wiley 2020-05-01
Series:Bioengineering & Translational Medicine
Subjects:
Online Access:https://doi.org/10.1002/btm2.10160