Caffeic acid and quercetin exert caspases-independent apoptotic effects on Leishmania major promastigotes, and reactivate the death of infected phagocytes derived from BALB/c mice

Caffeic acid and quercetin exert caspases-independent apoptotic effects on Leishmania major promastigotes, and reactivate the death of infected phagocytes derived from BALB/c mice

Objective: To investigate the leishmanicidal effects of two antioxidants, caffeic acid and quercetin on Leishmania major (L. major) promastigotes in vitro, and their immuno-modulatory effects on infected phagocytes derived from susceptible BALB/c mice. Methods: Caffeic acid and quercetin-induced cel...

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Bibliographic Details
Main Authors: Radia Belkhelfa-Slimani, Bahia Djerdjouri
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2017-04-01
Series:Asian Pacific Journal of Tropical Biomedicine
Subjects:
Apoptosis
Leishmania major
Phagocytes
iNOS
NF-κB
TNF-α
Online Access:http://www.sciencedirect.com/science/article/pii/S2221169116308838

Internet

http://www.sciencedirect.com/science/article/pii/S2221169116308838

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