A single amino acid mutation in SNAP-25 induces anxiety-related behavior in mouse.

A single amino acid mutation in SNAP-25 induces anxiety-related behavior in mouse.

Synaptosomal-associated protein of 25 kDa (SNAP-25) is a presynaptic protein essential for neurotransmitter release. Previously, we demonstrate that protein kinase C (PKC) phosphorylates Ser(187) of SNAP-25, and enhances neurotransmitter release by recruiting secretory vesicles near to the plasma me...

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Bibliographic Details
Main Authors: Masakazu Kataoka, Saori Yamamori, Eiji Suzuki, Shigeru Watanabe, Taku Sato, Hitoshi Miyaoka, Sadahiro Azuma, Shiro Ikegami, Reiko Kuwahara, Rika Suzuki-Migishima, Yohko Nakahara, Itsuko Nihonmatsu, Kaoru Inokuchi, Yuko Katoh-Fukui, Minesuke Yokoyama, Masami Takahashi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3176821?pdf=render

Internet

http://europepmc.org/articles/PMC3176821?pdf=render

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