Lack of Association of Multidrug Resistance Gene-1 Polymorphisms with Treatment Outcome in Chronic Myeloid Leukemia Patients Treated with Imatinib

Lack of Association of Multidrug Resistance Gene-1 Polymorphisms with Treatment Outcome in Chronic Myeloid Leukemia Patients Treated with Imatinib

Background: Despite the impressive results obtained with imatinib, inadequate response or resistance are observed in certain patients. It is known that imatinib is a substrate of a multidrug resistance gene (MDR1). Thus, interindividual genetic differences linked to single nucleotide polymorphism...

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Bibliographic Details
Main Authors: Yaya Kassogue, Hind Dehbi, Meryem Quachouh, Asma Quessar, Said Benchekroun, Sellama Nadifi
Format: Article
Language:English
Published: Shiraz University of Medical Sciences 2015-10-01
Series:Middle East Journal of Cancer
Subjects:
MDR1 polymorphisms
Chronic myeloid leukemia
Imatinib mesylate
Online Access:http://mejc.sums.ac.ir/index.php/mejc/article/view/269/228

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http://mejc.sums.ac.ir/index.php/mejc/article/view/269/228

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