Metastasis-inducing S100A4 and RANTES cooperate in promoting tumor progression in mice.

The tumor microenvironment has been described as a critical milieu determining tumor growth and metastases. A pivotal role of metastasis-inducing S100A4 in the development of tumor stroma has been proven in animal models and verified in human breast cancer biopsies. Expression and release of S100A4...

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Bibliographic Details
Main Authors: Birgitte Forst, Matilde Thye Hansen, Jörg Klingelhöfer, Henrik Devitt Møller, Gitte Helle Nielsen, Birgitte Grum-Schwensen, Noona Ambartsumian, Eugene Lukanidin, Mariam Grigorian
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-04-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2860983?pdf=render