Determination of the Potential Tumor-Suppressive Effects of <i>Gsdme</i> in a Chemically Induced and in a Genetically Modified Intestinal Cancer Mouse Model

Determination of the Potential Tumor-Suppressive Effects of <i>Gsdme</i> in a Chemically Induced and in a Genetically Modified Intestinal Cancer Mouse Model

<i>Gasdermin E</i> (<i>GSDME</i>), also known as <i>deafness autosomal dominant 5</i> (<i>DFNA5</i>) and previously identified to be an inducer of regulated cell death, is frequently epigenetically inactivated in different cancer types, suggesting that...

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Bibliographic Details
Main Authors: Lieselot Croes, Erik Fransen, Marieke Hylebos, Kimberly Buys, Christophe Hermans, Glenn Broeckx, Marc Peeters, Patrick Pauwels, Ken Op de Beeck, Guy Van Camp
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Cancers
Subjects:
Gsdme
Dfna5
knockout
mouse model
colorectal cancer
intestinal cancer
Apc
AOM
azoxymethane
inflammation
Online Access:https://www.mdpi.com/2072-6694/11/8/1214

Internet

https://www.mdpi.com/2072-6694/11/8/1214

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