Topically Applied Etamsylate: A New Orphan Drug for HHT-Derived Epistaxis (Antiangiogenesis through FGF Pathway Inhibition)

Topically Applied Etamsylate: A New Orphan Drug for HHT-Derived Epistaxis (Antiangiogenesis through FGF Pathway Inhibition)

Hereditary hemorrhagic telangiectasia (HHT) is a vascular dysplasia characterized by recurrent and spontaneous epistaxis (nose bleeds), telangiectases on skin and mucosa, internal organ arteriovenous malformations, and dominant autosomal inheritance. Mutations in Endoglin and ACVRL1/ALK1, genes main...

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Bibliographic Details
Main Authors: Virginia Albiñana, Guillermo Giménez-Gallego, Angela García-Mato, Patricia Palacios, Lucia Recio-Poveda, Angel-M Cuesta, José-Luis Patier, Luisa-María Botella
Format: Article
Language:English
Published: Georg Thieme Verlag KG 2019-07-01
Series:TH Open
Subjects:
hht
endoglin
alk1
antiangiogenesis
etamsylate
epistaxis
fgf pathway
tgf-β signaling pathway
Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/s-0039-1693710

Internet

http://www.thieme-connect.de/DOI/DOI?10.1055/s-0039-1693710

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