Crystal structure of an apremilast ethanol hemisolvate hemihydrate solvatomorph

Crystal structure of an apremilast ethanol hemisolvate hemihydrate solvatomorph

The title compound, C22H24N2O7S·0.5C2H5OH·0.5H2O {systematic name: (S)-4-acetamido-2-[1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]isoindoline-1,3-dione ethanol hemisolvate hemihydrate}, is a novel solvatomorph of apremilast (AP), which is an inhibitor of phosphodiesterase 4 (PDE4) and is in...

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Bibliographic Details
Main Authors: Yun-Deng Wu, Xiao-Hong Liu, Jian Xu, Si-Han Zhang, Kun Shen, Ling Sun, Yong-Mei He, Yan Ma, Ai-Hua Zhang
Format: Article
Language:English
Published: International Union of Crystallography 2017-06-01
Series:Acta Crystallographica Section E: Crystallographic Communications
Subjects:
apremilast
PDE4
psoriatic arthritis
crystal structure
hydrogen bonding
solvatomorph
Online Access:http://scripts.iucr.org/cgi-bin/paper?S2056989017006661

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http://scripts.iucr.org/cgi-bin/paper?S2056989017006661

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