Myosin light chain kinase mediates intestinal barrier disruption following burn injury.

BACKGROUND: Severe burn injury results in the loss of intestinal barrier function, however, the underlying mechanism remains unclear. Myosin light chain (MLC) phosphorylation mediated by MLC kinase (MLCK) is critical to the pathophysiological regulation of intestinal barrier function. We hypothesize...

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Bibliographic Details
Main Authors: Chuanli Chen, Pei Wang, Qin Su, Shiliang Wang, Fengjun Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3329538?pdf=render