New Chloramphenicol Derivatives from the Viewpoint of Anticancer and Antimicrobial Activity

New Chloramphenicol Derivatives from the Viewpoint of Anticancer and Antimicrobial Activity

Over the last years, we have been focused on chloramphenicol conjugates that combine in their structure chloramphenicol base with natural polyamines, spermine, spermidine and putrescine, and their modifications. Conjugate <b>3</b>, with spermidine (SPD) as a natural polyamine linked to c...

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Bibliographic Details
Main Authors: Panagiota C. Giannopoulou, Dionissia A. Missiri, Georgia G. Kournoutou, Eleni Sazakli, Georgios E. Papadopoulos, Dionissios Papaioannou, George P. Dinos, Constantinos M. Athanassopoulos, Dimitrios L. Kalpaxis
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:Antibiotics
Subjects:
Chloramphenicol
polyamines
conjugates
mitochondrial ribosome
molecular dynamics simulations
antimicrobial activity
anticancer activity
protein biosynthesis
antibiotics
Online Access:https://www.mdpi.com/2079-6382/8/1/9

Internet

https://www.mdpi.com/2079-6382/8/1/9

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