Toll-like receptor agonist augments virus-like particle-mediated protection from Ebola virus with transient immune activation.

Toll-like receptor agonist augments virus-like particle-mediated protection from Ebola virus with transient immune activation.

Identifying safe and effective adjuvants is critical for the advanced development of protein-based vaccines. Pattern recognition receptor (PRR) agonists are increasingly being explored as potential adjuvants, but there is concern that the efficacy of these molecules may be dependent on potentially d...

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Bibliographic Details
Main Authors: Karen A O Martins, Jesse T Steffens, Sean A van Tongeren, Jay B Wells, Alison A Bergeron, Samuel P Dickson, John M Dye, Andres M Salazar, Sina Bavari
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3933660?pdf=render

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http://europepmc.org/articles/PMC3933660?pdf=render

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