Co-regulation of metabolic genes is better explained by flux coupling than by network distance.

To what extent can modes of gene regulation be explained by systems-level properties of metabolic networks? Prior studies on co-regulation of metabolic genes have mainly focused on graph-theoretical features of metabolic networks and demonstrated a decreasing level of co-expression with increasing n...

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Bibliographic Details
Main Authors: Richard A Notebaart, Bas Teusink, Roland J Siezen, Balázs Papp
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS Computational Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/18225949/pdf/?tool=EBI