Biodistribution and Immunogenicity of Allogeneic Mesenchymal Stem Cells in a Rat Model of Intraarticular Chondrocyte Xenotransplantation

Biodistribution and Immunogenicity of Allogeneic Mesenchymal Stem Cells in a Rat Model of Intraarticular Chondrocyte Xenotransplantation

Xenogeneic chondrocytes and allogeneic mesenchymal stem cells (MSC) are considered a potential source of cells for articular cartilage repair. We here assessed the immune response triggered by xenogeneic chondrocytes when injected intraarticularly, as well as the immunoregulatory effect of allogenei...

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Bibliographic Details
Main Authors: Maribel Marquina, Javier A. Collado, Magdiel Pérez-Cruz, Pablo Fernández-Pernas, Juan Fafián-Labora, Francisco J. Blanco, Rafael Máñez, María C. Arufe, Cristina Costa
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-11-01
Series:Frontiers in Immunology
Subjects:
xenotransplantation
chondrocytes
alloimmunity
mesenchymal stem cells
immune rejection
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01465/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.01465/full

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