Senescence in Monocytes Facilitates Dengue Virus Infection by Increasing Infectivity

Senescence in Monocytes Facilitates Dengue Virus Infection by Increasing Infectivity

Aging and chronic condition increase the incidence of dengue virus (DENV) infection, generally through a mechanism involving immunosenescence; however, the alternative effects of cellular senescence, which alters cell susceptibility to viral infection, remain unknown. Human monocytic THP-1 cells (AT...

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Bibliographic Details
Main Authors: Tzu-Han Hsieh, Tsung-Ting Tsai, Chia-Ling Chen, Ting-Jing Shen, Ming-Kai Jhan, Po-Chun Tseng, Chiou-Feng Lin
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
dengue virus
senescence
IL-10
DC-SIGN
monocytes
Online Access:https://www.frontiersin.org/article/10.3389/fcimb.2020.00375/full

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https://www.frontiersin.org/article/10.3389/fcimb.2020.00375/full

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