Proximal Tubule Cell Hypothesis for Cardiorenal Syndrome in Diabetes

Incidence of cardiovascular disease (CVD) is remarkably high among patients with chronic kidney disease (CKD), even in the early microalbuminuric stages with normal glomerular filtration rates. Proximal tubule cells (PTCs) mediate metabolism and urinary excretion of vasculotoxic substances via apica...

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Bibliographic Details
Main Authors: Akihiko Saito, Ryohei Kaseda, Michihiro Hosojima, Hiroyoshi Sato
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:International Journal of Nephrology
Online Access:http://dx.doi.org/10.4061/2011/957164