Human Exportin-1 is a Target for Combined Therapy of HIV and AIDS Related Lymphoma

Human Exportin-1 is a Target for Combined Therapy of HIV and AIDS Related Lymphoma

Infection with HIV ultimately leads to advanced immunodeficiency resulting in an increased incidence of cancer. For example primary effusion lymphoma (PEL) is an aggressive non-Hodgkin lymphoma with very poor prognosis that typically affects HIV infected individuals in advanced stages of immunodefic...

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Bibliographic Details
Main Authors: Eline Boons, Els Vanstreels, Maarten Jacquemyn, Tatiane C. Nogueira, Jasper E. Neggers, Thomas Vercruysse, Joost van den Oord, Sharon Tamir, Sharon Shacham, Yosef Landesman, Robert Snoeck, Christophe Pannecouque, Graciela Andrei, Dirk Daelemans
Format: Article
Language:English
Published: Elsevier 2015-09-01
Series:EBioMedicine
Subjects:
Exportin-1
CRM1
XPO1
Small-molecule inhibitors
HIV
AIDS-related lymphoma
Primary effusion lymphoma
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396415300931

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http://www.sciencedirect.com/science/article/pii/S2352396415300931

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