CD8 PD-1 T-cells and PD-L1 circulating tumor cells in chemotherapy-naïve non-small cell lung cancer: towards their clinical relevance?

Background: Since tumor cells may escape from immune surveillance through the programmed cell death 1 (PD-1)/programmed death ligand (PD-L)1 axis, this study was designed in order to evaluate whether there is a correlation between the levels of PD-1 + and PD-L1 + -expressing immune cells (ICs) and c...

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Main Authors: Athanasios Kotsakis, Galatea Kallergi, Despoina Aggouraki, Zaharoula Lyristi, Filippos Koinis, Eleni Lagoudaki, Anastasios Koutsopoulos, Vassilis Georgoulias, Eleni-Kyriaki Vetsika
Format: Article
Language:English
Published: SAGE Publishing 2019-06-01
Series:Therapeutic Advances in Medical Oncology
Online Access:https://doi.org/10.1177/1758835919853193