Modafinil abrogates methamphetamine-induced neuroinflammation and apoptotic effects in the mouse striatum.

Methamphetamine is a drug of abuse that can cause neurotoxic damage in humans and animals. Modafinil, a wake-promoting compound approved for the treatment of sleeping disorders, is being prescribed off label for the treatment of methamphetamine dependence. The aim of the present study was to investi...

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Bibliographic Details
Main Authors: Mariana Raineri, Betina Gonzalez, Belen Goitia, Edgar Garcia-Rill, Irina N Krasnova, Jean Lud Cadet, Francisco J Urbano, Veronica Bisagno
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3464292?pdf=render