Global gene expression profiling of individual human oocytes and embryos demonstrates heterogeneity in early development.

Early development in humans is characterised by low and variable embryonic viability, reflected in low fecundity and high rates of miscarriage, relative to other mammals. Data from assisted reproduction programmes provides additional evidence that this is largely mediated at the level of embryonic c...

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Bibliographic Details
Main Authors: Lisa Shaw, Sharon F Sneddon, Leo Zeef, Susan J Kimber, Daniel R Brison
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3661520?pdf=render