Hypoxia upregulates PGI-synthase and increases PGI2 release in human vascular cells exposed to inflammatory stimuli
Hypoxia affects vascular function and cell metabolism, survival, growth, and motility; these processes are partially regulated by prostanoids. We analyzed the effect of hypoxia and inflammation on key enzymes involved in prostanoid biosynthesis in human vascular cells. In human vascular smooth muscl...
Main Authors: | Mercedes Camacho, Cristina Rodríguez, Anna Guadall, Sonia Alcolea, Mar Orriols, José-Román Escudero, José Martínez-González, Luis Vila |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2011-04-01
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Series: | Journal of Lipid Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S002222752040906X |
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