Jejunal wall delivery of insulin via an ingestible capsule in anesthetized swine—A pharmacokinetic and pharmacodynamic study

Abstract Biotherapeutic agents must be administered parenterally to obtain therapeutic blood concentrations, lowering patient compliance and complicating care. An oral delivery platform (ODP) was developed to deliver drugs into the small intestinal wall. This proof‐of‐concept study was performed in...

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Bibliographic Details
Main Authors: Mir Hashim, Radhika Korupolu, Baber Syed, Kyle Horlen, Simret Beraki, Padma Karamchedu, Arvinder K. Dhalla, Rodolphe Ruffy, Mir Imran
Format: Article
Language:English
Published: Wiley 2019-10-01
Series:Pharmacology Research & Perspectives
Subjects:
Online Access:https://doi.org/10.1002/prp2.522