Detection and benchmarking of somatic mutations in cancer genomes using RNA-seq data
To detect functional somatic mutations in tumor samples, whole-exome sequencing (WES) is often used for its reliability and relative low cost. RNA-seq, while generally used to measure gene expression, can potentially also be used for identification of somatic mutations. However there has been little...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
PeerJ Inc.
2018-07-01
|
Series: | PeerJ |
Subjects: | |
Online Access: | https://peerj.com/articles/5362.pdf |