Detection and benchmarking of somatic mutations in cancer genomes using RNA-seq data

To detect functional somatic mutations in tumor samples, whole-exome sequencing (WES) is often used for its reliability and relative low cost. RNA-seq, while generally used to measure gene expression, can potentially also be used for identification of somatic mutations. However there has been little...

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Bibliographic Details
Main Authors: Alexandre Coudray, Anna M. Battenhouse, Philipp Bucher, Vishwanath R. Iyer
Format: Article
Language:English
Published: PeerJ Inc. 2018-07-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/5362.pdf