Enamelin is critical for ameloblast integrity and enamel ultrastructure formation.

Enamelin is critical for ameloblast integrity and enamel ultrastructure formation.

Mutations in the human enamelin gene cause autosomal dominant hypoplastic amelogenesis imperfecta in which the affected enamel is thin or absent. Study of enamelin knockout NLS-lacZ knockin mice revealed that mineralization along the distal membrane of ameloblast is deficient, resulting in no true e...

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Bibliographic Details
Main Authors: Jan C-C Hu, Yuanyuan Hu, Yuhe Lu, Charles E Smith, Rangsiyakorn Lertlam, John Timothy Wright, Cynthia Suggs, Marc D McKee, Elia Beniash, M Enamul Kabir, James P Simmer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3945975?pdf=render

Internet

http://europepmc.org/articles/PMC3945975?pdf=render

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