Low Expression of ADCY4 Predicts Worse Survival of Lung Squamous Cell Carcinoma Based on Integrated Analysis and Immunohistochemical Verification

Low Expression of ADCY4 Predicts Worse Survival of Lung Squamous Cell Carcinoma Based on Integrated Analysis and Immunohistochemical Verification

PurposeThe molecular mechanism underlying the carcinogenesis and development of lung squamous cell carcinoma (LUSC) has not been sufficiently elucidated. This analysis was performed to find pivotal genes and explore their prognostic roles in LUSC.MethodsA microarray dataset from GEO (GSE19188) and a...

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Bibliographic Details
Main Authors: Zhicong Liu, Lixin Ru, Zhenchao Ma
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Oncology
Subjects:
lung squamous cell carcinoma
differential gene expression analysis
weighted gene co-expression network analysis
protein-protein interaction network
immunohistochemistry
survival analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.637733/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.637733/full

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