Evaluation of the suitability of free-energy minimization using nearest-neighbor energy parameters for RNA secondary structure prediction

<p>Abstract</p> <p>Background</p> <p>A detailed understanding of an RNA's correct secondary and tertiary structure is crucial to understanding its function and mechanism in the cell. Free energy minimization with energy parameters based on the nearest-neighbor mode...

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Bibliographic Details
Main Authors: Cobaugh Christian W, Cannone Jamie J, Doshi Kishore J, Gutell Robin R
Format: Article
Language:English
Published: BMC 2004-08-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/5/105