Fibroblast growth factor signaling potentiates VE-cadherin stability at adherens junctions by regulating SHP2.

The fibroblast growth factor (FGF) system plays a critical role in the maintenance of vascular integrity via enhancing the stability of VE-cadherin at adherens junctions. However, the precise molecular mechanism is not well understood. In the present study, we aimed to investigate the detailed mecha...

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Bibliographic Details
Main Authors: Kunihiko Hatanaka, Anthony A Lanahan, Masahiro Murakami, Michael Simons
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3358251?pdf=render