Distinct pathways of solid-to-solid phase transitions induced by defects: the case of dl-methionine

Distinct pathways of solid-to-solid phase transitions induced by defects: the case of dl-methionine

Understanding of solid-to-solid phase transition mechanisms in polymorphic systems is of critical importance for rigorous control over polymorph purity in the pharmaceutical industry to achieve the desired bioavailability and efficacy of drugs. Ubiquitous defects in crystals may play an important ro...

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Bibliographic Details
Main Authors: Genpei Shi, Si Li, Peng Shi, Junbo Gong, Mingtao Zhang, Weiwei Tang
Format: Article
Language:English
Published: International Union of Crystallography 2021-07-01
Series:IUCrJ
Subjects:
polymorphs
solid-to-solid phase transitions
crystal defects
cooperative molecular motion
nucleation and growth
polymorphism
pharmaceutical solids
Online Access:http://scripts.iucr.org/cgi-bin/paper?S2052252521004401

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http://scripts.iucr.org/cgi-bin/paper?S2052252521004401

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