The Negative Effect of Protein Phosphatase Z1 Deletion on the Oxidative Stress Tolerance of <i>Candida albicans</i> Is Synergistic with Betamethasone Exposure

The Negative Effect of Protein Phosphatase Z1 Deletion on the Oxidative Stress Tolerance of <i>Candida albicans</i> Is Synergistic with Betamethasone Exposure

The glucocorticoid betamethasone (BM) has potent anti-inflammatory and immunosuppressive effects; however, it increases the susceptibility of patients to superficial <i>Candida</i> infections. Previously we found that this disadvantageous side effect can be counteracted by menadione sodi...

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Bibliographic Details
Main Authors: Ágnes Jakab, Tamás Emri, Kinga Csillag, Anita Szabó, Fruzsina Nagy, Edina Baranyai, Zsófi Sajtos, Dóra Géczi, Károly Antal, Renátó Kovács, Krisztina Szabó, Viktor Dombrádi, István Pócsi
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Journal of Fungi
Subjects:
antifungal therapy
<i>Candida albicans</i>
combinatorial stress
glucocorticoid
menadione
oxidative stress
Online Access:https://www.mdpi.com/2309-608X/7/7/540

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https://www.mdpi.com/2309-608X/7/7/540

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