Class 2 CRISPR/Cas: an expanding biotechnology toolbox for and beyond genome editing

Class 2 CRISPR/Cas: an expanding biotechnology toolbox for and beyond genome editing

Abstract Artificial nuclease-dependent DNA cleavage systems (zinc-finger nuclease, ZFN; transcription activator like effectors, TALENs) and exogenous nucleic acid defense systems (CRISPR/Cas) have been used in the new era for genome modification. The most widely used toolbox for genome editing, modu...

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Bibliographic Details
Main Authors: Yuyi Tang, Yan Fu
Format: Article
Language:English
Published: BMC 2018-11-01
Series:Cell & Bioscience
Subjects:
Genome editing
Transcriptional repression
Diagnostic detection
CRISPR
Cas9
Cas12a
Online Access:http://link.springer.com/article/10.1186/s13578-018-0255-x

Internet

http://link.springer.com/article/10.1186/s13578-018-0255-x

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