Lassa Virus Vaccine Candidate ML29 Generates Truncated Viral RNAs Which Contribute to Interfering Activity and Attenuation

Defective interfering particles (DIPs) are naturally occurring products during virus replication in infected cells. DIPs contain defective viral genomes (DVGs) and interfere with replication and propagation of their corresponding standard viral genomes by competing for viral and cellular resources,...

Full description

Bibliographic Details
Main Authors: Dylan M. Johnson, Beatrice Cubitt, Tia L. Pfeffer, Juan Carlos de la Torre, Igor S. Lukashevich
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/13/2/214