Identification of Serum-Based Metabolic Feature and Characteristic Metabolites in Paraquat Intoxicated Mouse Models

Identification of Serum-Based Metabolic Feature and Characteristic Metabolites in Paraquat Intoxicated Mouse Models

Paraquat (PQ) is a widely used herbicide which can cause high mortality to humans. However, relatively few studies focus on metabolic feature of PQ intoxication for investigating the underlying mechanisms. Here we performed non-targeted metabolomics profiling of serum samples from acute and chronic...

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Bibliographic Details
Main Authors: Youjia Yu, Zishan Gao, Jiaqian Lou, Zhengsheng Mao, Kai Li, Chunyan Chu, Li Hu, Zheng Li, Chuwei Deng, Hanting Fan, Peng Chen, Huijie Huang, Yanfang Yu, Jingjing Ding, Ding Li, Feng Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Physiology
Subjects:
paraquat
intoxication
metabolomics
3-indolepropionic acid
2-hydroxybutyric acid
the ratio of L-serine/glycine
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2020.00065/full

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https://www.frontiersin.org/article/10.3389/fphys.2020.00065/full

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