JCPyV NCCR analysis in PML patients with different risk factors: exploring common rearrangements as essential changes for neuropathogenesis

JCPyV NCCR analysis in PML patients with different risk factors: exploring common rearrangements as essential changes for neuropathogenesis

Abstract Background During severe immunosuppression or treatment with specific biological drugs, human polyomavirus JC (JCPyV) may establish a lytic infection in oligodendrocytes, leading to progressive multifocal leukoencephalopathy (PML). Beyond AIDS, which represents the most common predisposing...

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Bibliographic Details
Main Authors: Maria Rosa Ciardi, Maria Antonella Zingaropoli, Marco Iannetta, Carla Prezioso, Valentina Perri, Patrizia Pasculli, Miriam Lichtner, Gabriella d’Ettorre, Marta Altieri, Antonella Conte, Valeria Pietropaolo, Claudio Maria Mastroianni, Vincenzo Vullo
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Virology Journal
Subjects:
HIV
Multiple sclerosis
CSF
CNS
Disease-modifying therapies
Online Access:https://doi.org/10.1186/s12985-020-1295-5

Internet

https://doi.org/10.1186/s12985-020-1295-5

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