Risk of major bleeding during extended oral anticoagulation in patients with first unprovoked venous thromboembolism: a systematic review and meta-analysis protocol

Abstract Background The optimal duration of anticoagulation after a first unprovoked venous thromboembolism (VTE) remains controversial. Deciding to stop or continue anticoagulant therapy indefinitely after completing 3 to 6 months of initial treatment requires balancing the long-term risk of recurr...

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Bibliographic Details
Main Authors: Faizan Khan, Miriam Kimpton, Tobias Tritschler, Grégoire Le Gal, Brian Hutton, Dean A. Fergusson, Marc A. Rodger
Format: Article
Language:English
Published: BMC 2019-10-01
Series:Systematic Reviews
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13643-019-1175-5