MicroRNA Expression Profiling of Bone Marrow–Derived Proangiogenic Cells (PACs) in a Mouse Model of Hindlimb Ischemia: Modulation by Classical Cardiovascular Risk Factors

MicroRNA Expression Profiling of Bone Marrow–Derived Proangiogenic Cells (PACs) in a Mouse Model of Hindlimb Ischemia: Modulation by Classical Cardiovascular Risk Factors

BackgroundClassical cardiovascular risk factors (CRFs) are associated with impaired angiogenic activities of bone marrow–derived proangiogenic cells (PACs) related to peripheral artery diseases (PADs) and ischemia-induced neovascularization. MicroRNAs (miRs) are key regulators of gene expression, an...

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Bibliographic Details
Main Authors: Michel Desjarlais, Sylvie Dussault, José Carlos Rivera, Sylvain Chemtob, Alain Rivard
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Genetics
Subjects:
microRNA (miR)
proangiogenic cell (PAC)
cardiovascular risk factors
hindlimb ischemia
neovascularization
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2020.00947/full

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https://www.frontiersin.org/article/10.3389/fgene.2020.00947/full

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