Remodeling of the methylation landscape in breast cancer metastasis.

The development of breast cancer metastasis is accompanied by dynamic transcriptome changes and dramatic alterations in nuclear and chromatin structure. The basis of these changes is incompletely understood. The DNA methylome of primary breast cancers contribute to transcriptomic heterogeneity and d...

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Bibliographic Details
Main Authors: Marsha Reyngold, Sevin Turcan, Dilip Giri, Kasthuri Kannan, Logan A Walsh, Agnes Viale, Marija Drobnjak, Linda T Vahdat, William Lee, Timothy A Chan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4118917?pdf=render