The Heterochromatic Barrier to DNA Double Strand Break Repair: How to Get the Entry Visa

The Heterochromatic Barrier to DNA Double Strand Break Repair: How to Get the Entry Visa

Over recent decades, a deep understanding of pathways that repair DNA double strand breaks (DSB) has been gained from biochemical, structural, biophysical and cellular studies. DNA non-homologous end-joining (NHEJ) and homologous recombination (HR) represent the two major DSB repair pathways, and bo...

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Bibliographic Details
Main Authors: Aaron A. Goodarzi, Penny A. Jeggo
Format: Article
Language:English
Published: MDPI AG 2012-09-01
Series:International Journal of Molecular Sciences
Subjects:
DNA non-homologous end-joining
chromatin
heterochromatin
damage response signaling
ataxia telangiectasia mutated
homologous recombination
Online Access:http://www.mdpi.com/1422-0067/13/9/11844

Internet

http://www.mdpi.com/1422-0067/13/9/11844

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