The histone deacetylase inhibitor Trichostatin A modulates CD4+ T cell responses
<p>Abstract</p> <p>Background</p> <p>Histone deacetylase inhibitors (HDACIs) induce hyperacetylation of core histones modulating chromatin structure and affecting gene expression. These compounds are also able to induce growth arrest, cell differentiation, and apoptotic...
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2003-11-01
|
Series: | BMC Cancer |
Online Access: | http://www.biomedcentral.com/1471-2407/3/30 |