The histone deacetylase inhibitor Trichostatin A modulates CD4+ T cell responses

<p>Abstract</p> <p>Background</p> <p>Histone deacetylase inhibitors (HDACIs) induce hyperacetylation of core histones modulating chromatin structure and affecting gene expression. These compounds are also able to induce growth arrest, cell differentiation, and apoptotic...

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Bibliographic Details
Main Authors: Moreira José, Scheipers Peter, Sørensen Poul
Format: Article
Language:English
Published: BMC 2003-11-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/3/30