A Helicobacter pylori Homolog of Eukaryotic Flotillin Is Involved in Cholesterol Accumulation, Epithelial Cell Responses and Host Colonization

A Helicobacter pylori Homolog of Eukaryotic Flotillin Is Involved in Cholesterol Accumulation, Epithelial Cell Responses and Host Colonization

The human pathogen Helicobacter pylori acquires cholesterol from membrane raft domains in eukaryotic cells, commonly known as “lipid rafts.” Incorporation of this cholesterol into the H. pylori cell membrane allows the bacterium to avoid clearance by the host immune system and to resist the effects...

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Bibliographic Details
Main Authors: Melanie L. Hutton, Kimberley D'Costa, Amanda E. Rossiter, Lin Wang, Lorinda Turner, David L. Steer, Seth L. Masters, Ben A. Croker, Maria Kaparakis-Liaskos, Richard L. Ferrero
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-06-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Helicobacter pylori
lipid rafts
membrane raft domains
cholesterol
bacterial flotillins
type IV secretion system
Online Access:http://journal.frontiersin.org/article/10.3389/fcimb.2017.00219/full

Internet

http://journal.frontiersin.org/article/10.3389/fcimb.2017.00219/full

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